Inspired by the UN鈥檚 Sustainable Development Goals, 国产乱伦鈥檚 Grand Challenges Programme launched in 2017 with an initial focus on five global challenges: climate change, global health, the food鈥揺nergy鈥搘ater nexus, a digitally transformed world and sustainable cities. We spoke to Mariette DiChristina, Executive Vice President of Editorial and Publishing for Nature Research Magazines and Editor-in-Chief of Scientific American, to get her insights into how the Grand Challenges Programme has grown over the past 18 months.